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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T36197 CAY10747

CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol .1It decreases protein levels of the Hsp90-Cdc37 complex and the Hsp90-Cdc37 clients phosphorylated Akt and Cdk4 in A549 cells when used at a concentration of 5 μM. CAY10747 inhibits proliferation of A549, MCF-7, HOS, and HepG2 cells (IC50s = 0.41, 0.64, 0.9, and 0.94 μM, respectively) and induces apoptosis in A549 cells. 1.Li, N., Xu,...

化合物

CAY10747
Cat.No: T36197
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00755 CRYAB Protein, Human, Recombinant (His)

α(B)-Crystallin,Alpha(B)-Crystallin,He...

Human E. coli
α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and or...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His)

GP180,B220,L-CA,protein tyrosine phosphata...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc)

SLAM family member 7,19A,SLAM7,CS1,CD319,CRACC

Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc)

GLUR6,EAA4,MRT6,GLR6,glutamate receptor, ionotropic, kainate...

Human HEK293 Cells
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar disorder (BPD). The gene coding for GRIK2 has been suggested as a candidate gene for autism based on its localization in the autism-specific region on chromosome 6q21 and the involvement of receptor protein in cognitive functions like learning and memory. GRIK2 belongs to the gl...
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated

CS1,SLAM7,CD319,SLAM family member 7,CRACC,19A

Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPJ-00854 ETS1 Protein, Human, Recombinant (His)

V-ets Erythroblastosis Virus E26 Oncogene Homolog 1...

Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death As...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

HDLQTL6,SR-BI,SRB1,CD36L1,CLA-1,CLA1,scave...

Human HEK293 Cells
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi)

MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,S...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated

SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,B

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

H-2K,OVA,MHC,H2-K1

Mouse HEK293 Cells
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01412 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

SARS-CoV-2 epitope,MHC

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01416 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,SARS-CoV-2 epitope

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

CRYAB Protein, Human, Recombinant (His)
Cat.No: TMPJ-00755
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (aa 1-529, His)
Cat.No: TMPY-05308
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05387
Species: Human
Expression System: HEK293 Cells
GRIK2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04318
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05547
Species: Human
Expression System: HEK293 Cells
ETS1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00854
Species: Human
Expression System: E. coli
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05498
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01357
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01363
Species: Human
Expression System: HEK293 Cells
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
Cat.No: TMPK-01413
Species: Mouse
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01412
Species: Human
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01416
Species: Human
Expression System: HEK293 Cells
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